| Movie | Role |
|---|---|
| WALL·E (2008) | Ship's Computer (voice) |
| Chappie (2015) | Michelle Bradley |
| Avatar (2009) | Dr. Grace Augustine |
| Prayers for Bobby (2009) | Mary Griffith |
| Ghostbusters II (1989) | Dana Barrett |
| Alien (1979) | Lt. Ellen Louise Ripley |
| Ghostbusters (1984) | Dana Barrett |
| Aliens (1986) | Lt. Ellen Louise Ripley |
| Avatar: The Way of Water (2022) | Kiri / Dr. Grace Augustine |
| Alien³ (1992) | Ripley |
| Holes (2003) | Louise Walker the Warden |
| Galaxy Quest (1999) | Gwen DeMarco |