| Movie | Role |
|---|---|
| The Wolf of Wall Street (2013) | Naomi Lapaglia |
| Suicide Squad (2016) | Harleen Quinzel / Harley Quinn |
| Barbie (2023) | Barbie, Producer |
| The Suicide Squad (2021) | Harleen Quinzel / Harley Quinn |
| Once Upon a Time… in Hollywood (2019) | Sharon Tate |
| Birds of Prey (and the Fantabulous Emancipation of One Harley Quinn) (2020) | Harleen Quinzel / Harley Quinn, Producer |
| Promising Young Woman (2020) | Producer |
| Babylon (2022) | Nellie LaRoy |
| Saltburn (2023) | Producer |