| Movie | Role |
|---|---|
| The Brothers Solomon (2007) | Janine |
| The Secret Life of Walter Mitty (2013) | Cheryl Melhoff |
| Will & Harper (2024) | Self |
| Extract (2009) | Suzie |
| Adventureland (2009) | Paulette |
| Masterminds (2016) | Kelly Campbell |
| Sausage Party (2016) | Brenda (voice) |
| The Martian (2015) | Annie Montrose |
| Despicable Me 3 (2017) | Lucy Wilde (voice) |
| Zoolander 2 (2016) | Alexanya Atoz |
| Paul (2011) | Ruth Buggs |
| Ghostbusters (2016) | Erin Gilbert |
| Wonder Woman 1984 (2020) | Barbara Ann Minerva / Cheetah, Barbara Minerva |
| Despicable Me 4 (2024) | Lucy (voice) |
| Bridesmaids (2011) | Annie Walker, Screenplay |
| Walk Hard: The Dewey Cox Story (2007) | Edith |
| Despicable Me 2 (2013) | Lucy (voice) |