1. Good morning.
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2. That's your third ding.
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3. Good morning. It's Carly.
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4. She has arrived at her pathology conference.
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5. Hmm.
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6. Hmm.
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7. Shaun, you need to text her back.
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8. Her text wasn't a question. It doesn't require a response.
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9. True. But it sucks to be left hanging.
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10. You didn't like how it felt
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11. when you thought Carly was ignoring you.
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12. I have received your message.
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13. Sent.
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14. Hmm.
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15. You made me breakfast?
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16. Oh, God, no. I ordered breakfast.
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17. But I managed to keep it warm.
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18. You don't have to do this. I'm fine.
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19. Did you get any sleep?
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20. I got enough.
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21. Her death's not your fault.
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22. She knew the risks.
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23. She made a choice to save her baby.
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24. I bet she'd make the same choice again,
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25. even knowing how it would end.
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26. Thank you.
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27. Thanks for breakfast.
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28. We do a complete enucleation of the right eye,
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29. then replace it with the temporary implant,
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30. and in a few weeks, you'll...
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31. You know why blind people don't skydive?
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32. It scares the hell out of the dog.
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33. Let the doctors finish. Okay, bud?
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34. Yeah, cancer eye out. Fake eye in.
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35. Just like last time. I got it.
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36. Check it out.
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37. It even moves and everything.
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38. You can't even tell it's fake.
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39. Very cool. Like a bionic superhero.
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40. Yeah, and my superpower is tripping over stuff.
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41. What time is the surgery?
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42. 00.
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43. Which means I've got six hours left
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44. to blast some aliens.
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45. If anyone utters the word "Bubble Girl,"
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46. I will transfer to a different hospital.
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47. When you were his age,
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48. would you have faced going blind with h-humor,
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49. maturity, and acceptance?
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50. I would have burned things down.
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51. He's dealing with it in his own way.
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52. We'll check in with him
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53. while you're taking care of the rest of the paperwork.
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54. Make sure Charlie knows there's people he can talk to.
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55. Thank you. Thank you.
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56. Dr. Reznick, take Charlie's blood to the lab.
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57. Dr. Browne, talk to him.
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58. Maybe he'll open up to you.
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59. Heart sounds are normal. No sign of pericardial effusion.
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60. You are the oldest SCID-patient I am aware of.
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61. People with your condition usually die very young.
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62. Yay. I win.
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63. Tara, imaging confirms that you have infected tissue on your right lung,
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64. that's what's causing your breathing issues.
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65. And we're gonna remove it with a procedure called decortication...
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66. And you'll use the thoracoscopic approach
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67. to decrease risk of infection.
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68. And I'll be in an enclosed chamber in the O.R. What else?
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69. I assure you, we'll be taking every precaution to keep you safe.
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70. Dr. Melendez, this building is a glorified incubator
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71. for every infection on the planet.
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72. Considering I don't come with an immune system,
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73. I don't need assurances.
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74. I need you to tell me how you're gonna not kill me.
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75. We will administer a course
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76. of broad-spectrum antibiotics.
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77. You will be transported to the O.R. under a respiratory hood.
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78. The room will be equipped with laminar air flow
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79. and kept at a positive pressure of 8 Pascals.
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80. Surgical instruments will be double-sterilized
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81. and all blood products will be irradiated.
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82. Thank you, Dr. Murphy.
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83. Visitors will also have to go through a strict decontamination...
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84. There won't be any.
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85. The less time I spend with people, the better.
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86. Are we done?
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87. How'd your talk with Charlie go?
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88. He wants to be left alone.
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89. No, you want to be left alone. And yet here we are.
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90. Precocious pre-teen going blind.
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91. Come on, that's Claire catnip. You have to talk to him.
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92. Did he have any tests scheduled? No.
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93. No one's seen him, heard him, smelled him. I'm calling Security.
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94. Hold on. What are you doing?
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95. Where's Charlie?
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96. Did something happen? Is he okay?
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97. He's in imaging.
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98. We'll have him back very soon.
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99. He ordered a ride 15 minutes ago.
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100. To where? It's close.
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101. We could have him back before anyone knows he's gone.
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102. Are you insane? You're right.
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103. It's much better if we go back in there
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104. and freak out two already-freaked-out parents,
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105. and while you're at it, explain to Andrews
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106. that you didn't do what he asked you to do.
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107. Hmm.
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108. Which emoji was it?
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109. Just send it to me.
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110. Oh...
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111. You told me I have to respond.
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112. There is no response to...
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113. Okay, I think Carly's saying she misses you
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114. and wants to know that you miss her, too.
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115. You know all of that from one fake face?
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116. Just text her back something flirty, casual.
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117. Say something like, "I can't stop thinking about you."
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118. I have stopped thinking about her many times today.
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119. Do not text Carly that.
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120. I have to go.
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121. Okay.
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122. This popcorn is terrible.
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123. We have to get you back before your parents start to worry.
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124. We're gonna be three years, five months too late.
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125. The game is a blowout. So, we leave now...
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126. What's her name?
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127. What?
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128. I dunno.
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129. The only words I've ever said to her are,
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130. "Can I have a slushy?"
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131. I just wanted to see her one last time.
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132. Go say hi. Are you crazy?
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133. I was asking her that earlier.
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134. Tell her you think she's the most beautiful girl you've ever laid eyes on,
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135. and with your last few hours of sight,
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136. you wanted to see her face one more time.
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137. As lovely as this is... Don't ruin the moment.
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138. The necrotic debris has completely encased the visceral pleura.
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139. DR. Follow me with the camera. I don't want to spring a leak.
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140. Tissue's fused her lungs to her chest wall.
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141. I need the Kaiser Forceps.
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142. Damn it.
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143. Tissue's too thick to fit through the ports.
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144. We need to do a thoracotomy.
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145. And we can't open her up in an air-tight chamber.
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146. If we have to cauterize a bleed,
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147. the whole thing could explode.
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148. We have to take our Bubble Girl out of the bubble.
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149. Lemonade! Get your ice-cold lemonade!
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150. We've been gone too long.
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151. Calm down. It'll take the kid 15 seconds to chicken out.
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152. Or less.
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153. I'm a wuss.
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154. Most kids wouldn't have gone over at all. Good for you.
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155. Can I... No.
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156. I'm just... No.
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157. It better be fast. What?
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158. We're giving a sad, nearly blind kid
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159. a few more minutes in the sun.
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160. We could get an award for this.
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161. DR. Change gloves every 20 minutes.
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162. We need to be fast, but extremely careful.
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163. Knife.
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164. It's a Northern flying squirrel.
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165. They don't fly so much as glide.
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166. You're lucky it's not infected.
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167. Well, it's a fascinating species.
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168. They're uncommonly high-strung for a nocturnal rodent.
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169. Is the squirrel in the bag?
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170. Yes.
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171. Henry comes everywhere... No, no, no, no, no.
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172. That's okay. I don't need to see him.
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173. Okay.
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174. Has he bitten you before?
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175. It was my fault. I provoke him.
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176. Henry's a good boy.
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177. It's not your fault.
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178. You can't take him from me.
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179. He's not allowed to hurt you.
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180. Hi. It's47.
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181. Thank you.
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182. You're 17 minutes late for your30...
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183. Mrs. Pryce and I need to have a little talk.
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184. It's okay. Henry and I are fine.
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185. Who's Henry?
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186. You hesitated before cutting her open.
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187. We had to work fast once I made the incision.
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188. I was running through the procedure in my head.
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189. There's no shame in needing to process a tough loss.
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190. You should talk to someone.
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191. I'd prefer to focus on my current patient
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192. rather than my last one.
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193. Hey. Dr. Browne, where's my patient?
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194. And before you say, "Imaging,"
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195. I already know that's not true.
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196. He's with me and Morgan.
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197. He just needed to process a few things. Everything's...
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198. Watch out!
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199. What's going on?
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200. Morgan just missed a turn. She's a terrible driver.
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201. Uh, no, we're on our way back now.
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202. Hurry. Okay.
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203. How long was I out in the open?
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204. Thirteen minutes.
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205. We got all of the infected tissue.
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206. That's annoying.
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207. It was necessary to save your life.
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208. No, I meant your phone.
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209. Oh. It is.
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210. I bet it's your girlfriend.
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211. How did you know?
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212. Only annoying girlfriends text that much.
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213. I used to text my boyfriend all the time.
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214. It annoyed him, too.
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215. I am supposed to flirt with her,
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216. and I don't know how.
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217. Did your boyfriend break up with you
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218. because you were annoying?
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219. No. He died.
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220. That's the downside of outliving your prognosis.
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221. You outlive everyone else's too.
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222. That is a downside.
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223. Get out your phone.
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224. Hmm.
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225. I'll tell you what to type.
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226. I'm really good at phone sex.
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227. It's the only kind of sex I can have.
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228. We haven't had sex.
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229. I'll stick to foreplay.
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230. No, thank you.
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231. Do you text your parents? Or are they dead too?
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232. My parents are in Denver.
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233. My dad's job transferred them there.
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234. They always wanted to live near the snow.
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235. They're outdoorsy, and I'm, you know, not.
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236. I am not close to my parents either.
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237. I have autism, and they don't.
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238. I need to listen to your lungs.
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239. I just got really dizzy.
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240. What's going on?
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241. You have an infection.
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242. Temperature is 103.6. BP is 80/50.
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243. She's showing early signs of sepsis.
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244. Start her on a course of IV immunoglobulin therapy,
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245. ADA-enzyme replacement and GM-CSF.
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246. Okay.
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247. I think we can do more than treat her infection...
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248. Gene replacement therapy.
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249. We harvest her stem cells and use a retroviral vector
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250. to transduce her DNA with the modified ADA gene.
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251. If it works, she's cured.
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252. And if it doesn't work, she dies.
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253. There's a 50% chance her body will have an acute toxic reaction.
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254. We're going to treat the infection.
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255. She'll get another infection.
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256. And another, and another,
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257. and eventually, one of them will kill her.
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258. You don't know that. She's already beaten the odds.
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259. By cutting herself off from the world.
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260. Traditional treatment is the safer course.
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261. He's blowing off steam.
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262. He's with the doctors. He's safe.
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263. He's scared and overwhelmed,
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264. and obviously he felt like he couldn't tell us...
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265. Because you've been keeping him under lock and key.
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266. I'm protecting him.
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267. We have to stay strong.
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268. I think Charlie knows you're strong.
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269. And he knows you love him.
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270. But the moment you all heard the word "cancer,"
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271. everything in Charlie's life changed.
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272. And I think he needs to know that, at some point,
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273. it's going to start to feel like his life again.
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274. My mom and dad used to do these things called
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275. spontaneous family adventure days...
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276. SFADs.
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277. They were pretty lame. But they let me skip school.
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278. Got to go to baseball games,
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279. drive around with blaring music.
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280. I got to eat food that was inorganic and genetically modified.
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281. Sometimes I even got to stay up past midnight.
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282. Now we go to doctor's appointments.
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283. And my mom makes lists.
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284. And cries.
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285. And my dad's... quiet.
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286. Just one more quick stop.
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287. Morgan, Andrews is expecting us to...
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288. Please, just 20 more minutes.
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289. Fifteen.
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290. Park told me you rejected his gene therapy idea.
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291. We can't dismiss possible treatment options out of fear.
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292. It's not fear.
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293. It's a reasonable degree of caution.
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294. Since when are you cautious?
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295. The benefit of the cure may be worth the risk.
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296. Let Park take it to her.
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297. No. It's not worth it.
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298. The cure is riskier in the short term,
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299. but the long-term upside is much greater.
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300. We can give you the chance to live a long, healthy, normal life.
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301. No, you can't.
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302. I've been a freak my whole life.
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303. And curing my disease, letting me take a breath of fresh air,
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304. it's not gonna make me normal.
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305. Increase the oxygen to 15 liters.
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306. Start her on the IVIG.
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307. We need to let her rest.
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308. I'm a freak, too.
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309. People have called me that
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310. because I am not neurotypical.
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311. And I used to be alone,
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312. like you.
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313. Sometimes that was easier.
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314. Because it is hard to be around people
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315. when you're not like them.
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316. But now I have Dr. Glassman,
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317. and a roommate who is a girl,
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318. and a girlfriend who is only annoying some of the time.
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319. And I think it is better than being alone.
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320. If you're... cured,
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321. you can be..."outdoorsy"
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322. like your parents.
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323. Or you can stay inside and have phone sex.
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324. It will be your choice.
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325. The next time you go over my head will be the last.
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326. Prep her for the gene replacement.
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327. Nice work, Shaun.
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328. No. No way.
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329. He's going blind.
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330. It's his last chance to see a naked woman.
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331. You're a woman.
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332. I bet under those clothes, you're a naked one.
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333. I'm his sister.
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334. I'll slip you 50 bucks.
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335. My budget proposal, for your approval.
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336. Surgical cases, for your review.
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337. Before the board meeting tomorrow night.
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338. The pregnant woman...
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339. How's Neil taking it?
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340. Five minutes, please. I'm with Dr. Lim.
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341. I see there's a new member on the clinic team.
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342. How's that going?
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343. Well, it's been half-a-day. We're working out the kinks.
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344. Well, if it's still smooth-sailing by close of business,
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345. let me know your secret.
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346. I guess that answers my initial question.
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347. He keeps telling me he's fine.
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348. You're the last person he'd tell if he weren't.
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349. I'd be the second to last.
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350. I'm almost done.
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351. You're the President.
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352. He has to listen when you talk. Or, pretend to.
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353. Hey, the four-year-old with the ear infection has been here half an hour,
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354. his mother just pulled out fingerpaints.
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355. You need to go.
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356. Debbie, this is Dr. Lim, Chief of Surgery.
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357. I know. It's very impressive.
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358. Come back if you get an ear infection.
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359. One more. No.
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360. We're done.
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361. The surgery can't start without me.
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362. Where are we going next? Yosemite? The Great Wall?
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363. The top of Everest? It's never gonna be enough.
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364. Claire, stop.
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365. You can't pack a lifetime of things you're gonna miss into one day.
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366. Your situation sucks, and it is unfair.
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367. But you know what, life sucks, and it's unfair,
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368. and things end before we're ready.
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369. We are going back. Now.
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370. No.
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371. I'm not gonna have the surgery.
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372. How long before I know
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373. if I've let you talk me into something really stupid?
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374. You could have an acute toxic reaction and die
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375. in the next 24 hours.
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376. But we hope to see some positive sign your body is responding soon.
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377. Okay.
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378. Your transfusion is done. We'll check on you in a half-hour.
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379. Dr. Murphy.
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380. Would you... Sit with me?
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381. What do you want to know?
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382. Nothing. I...
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383. I just want someone to be here.
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384. In case I croak.
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385. Hmm.
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386. It's probably all your annoying girlfriend wants, too.
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387. Just to know you're there.
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388. Carly's in good health and unlikely to die soon.
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389. Some girls have all the luck.
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390. Debbie!
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391. You bellowed?
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392. This thing is broken.
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393. Can you call someone from I.T. and send them over, please?
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394. Oh, I meant to tell you that I, um, upgraded our software.
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395. It's gonna be faster, more efficient.
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396. Not if I don't know how to use it.
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397. You can't just change my entire software system without asking me.
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398. I didn't change it. I upgraded it.
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399. There.
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400. Or kick out my Chief of Surgery.
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401. Or interrupt my appointments.
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402. You'll be here 20 hours a day
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403. if you don't stick to a schedule.
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404. It's my call.
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405. I'm not here to slap on Band-Aids
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406. or to write prescriptions.
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407. That woman had serious issues we needed to discuss.
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408. The one with the rodent in her purse?
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409. It's a squirrel. It's a Northern flying squirrel.
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410. You weren't gonna fix whatever issues she has
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411. with an extra five minutes.
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412. It's my clinic, okay? I decide how it runs!
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413. Okay.
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414. I thought that you wanted me to be a part of it.
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415. You know, to actually help and to...
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416. Make changes, have opinions.
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417. But if that's not what you want, then I...
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418. I should do what I promised...
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419. I quit.
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420. You're out of sutures.
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421. I'm sorry.
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422. I... I shouldn't have said any of that.
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423. I lost somebody recently.
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424. And it hurts.
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425. A lot.
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426. And I took it out on you, and that is unfair.
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427. But if you don't have this surgery,
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428. you won't ever drink another slushy at a baseball game.
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429. Or feel the wind in your hair when you speed down the road.
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430. Or...
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431. Or touch a naked woman.
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432. Now, this sucks.
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433. It really, really sucks.
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434. But it will get less sucky.
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435. And the part that hurts so much right now
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436. will start to hurt less.
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437. And life goes on,
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438. and you will have wonderful moments,
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439. and you will have sucky moments.
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440. And it will be your life.
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441. And it'll be a good life, Charlie.
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442. I suspect it might even be a great life.
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443. Oh, thank God.
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444. DR. Sorry it took a while.
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445. Car trouble.
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446. DR. Welcome back, Charlie.
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447. You had some good people very worried.
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448. I'm really sorry.
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449. You guys can ground me forever for this, but I just...
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450. I just wanted to have one last day of fun.
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451. We can be fun, too. Again.
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452. I was thinking
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453. it might be time to reintroduce the SFADs.
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454. Baseball games, concerts, staying up late.
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455. That sounds pretty lame.
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456. We're running a little late,
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457. and we need to get you prepped.
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458. I'm sorry. I need some 5-0 nylon sutures.
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459. And apparently we need to talk.
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460. You can report back to the Chief of Surgery that I'm fine.
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461. You don't have to talk to me. You don't have to talk to her.
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462. But you need to talk to someone.
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463. I'm not a med student, Aaron. I've lost patients before.
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464. But you never lost someone who should have lived.
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465. No one would be fine. I wouldn't be.
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466. You're not fine.
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467. If for no other reason than your boss doesn't think so.
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468. And the bigger problem
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469. is your girlfriend agrees with her.
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470. We'll be right there as soon as you wake up.
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471. We love you so much.
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472. I love you, too.
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473. We'll take good care of him.
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474. Thank you.
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475. You ready?
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476. Yeah.
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477. I forgot to take his vitals.
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478. I'm sorry.
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479. Go ahead, I'll... I'll bring him out.
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480. I-I thought you already took my...
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481. Shut up.
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482. We're bringing the patient down now. Vitals okay?
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483. Temp might be a little up, but he's ready now.
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484. I just need you to count back from 10.
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485. Ten...
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486. Nine...
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487. Eight...
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488. Seven...
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489. Six...
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490. Five...
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491. You were right.
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492. I'm not fine.
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493. It's okay not to be fine.
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494. You can't blame yourself.
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495. I was the one holding the knife.
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496. The blame lies with me.
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497. But the responsibility is ours.
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498. Yours and... mine?
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499. Yes.
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500. You're not objective about me
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501. because of our relationship.
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502. If we weren't together,
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503. I'm not sure you would've agreed to let me do that surgery.
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504. You honestly believe I approved a procedure
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505. that I didn't think you could do
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506. because we're sleeping together?
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507. No. You thought I could do it.
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508. That's the problem.
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509. I think your personal feelings
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510. may have led you to overestimate me.
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511. You came to me.
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512. You sold me the surgery,
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513. told me that you could pull it off.
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514. And now I'm at fault because I believed that you...
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515. It's not about fault.
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516. It's about being aware
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517. so that this doesn't happen again.
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518. It will happen again.
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519. I will make decisions. You will have bad outcomes.
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520. That doesn't mean either of us was wrong.
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521. My approval had nothing to do with our relationship.
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522. We can't know that for sure.
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523. If we weren't dating, that woman might still be alive.
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524. And we both have to live with that.
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525. Mom?
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526. Dad?
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527. We're here, honey.
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528. We're right here.
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529. You did so good.
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530. We're so proud of you, buddy.
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531. DR. Charlie.
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532. It's Dr. Reznick. How are you feeling?
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533. Not awesome.
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534. Are you in any pain?
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535. No.
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536. No, I'm okay.
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537. I'll let you rest.
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538. Wait, Dr. Reznick.
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539. Yes?
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540. Thank you so much.
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541. For everything.
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542. You're welcome.
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543. And Dr. Browne?
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544. Dr. Browne, are you here?
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545. DR. Your T-cell count has increased.
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546. And your fever dropped to 99.3.
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547. Your body's fighting the infection.
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548. So, what does that mean? I'm cured?
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549. It's too early to use that word exactly.
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550. We'll need to keep you in isolation
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551. for a few more weeks to make sure
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552. that your immune system is developing on pace.
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553. And there is still a 5% to 7% chance of a toxic reaction.
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554. But yes, the cure appears to be working.
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555. You should tell your parents the good news.
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556. What are they gonna do? Feed me juice through a straw?
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557. They could just be here.
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558. I'm fine.
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559. Let us know if you need anything.
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560. I'll check in on you in the morning.
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561. Thank you.
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562. For not killing me.
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563. You're welcome.
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564. Oh, there is still a 5% to 7% chance of a...
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565. Shaun. She knows.
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566. Aaron, you... You do not owe me a gift.
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567. I owe you an apology.
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568. I was out of line today. I was pushing way too hard.
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569. It's not a gift.
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570. Oh...
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571. Is it punishment?
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572. Nurses swear by them.
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573. The arch supports are supposed to be spectacular.
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574. I'm not coming back to the clinic.
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575. It was a bad idea, terribly executed.
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576. Two of the smartest women I know,
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577. my wife and my new office manager,
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578. think that I need to make some changes.
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579. You wanted to help, you wanted to be a part of my life,
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580. I fought it.
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581. I proposed, and then I freaked out.
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582. Mm-hmm. We got married...
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583. You freaked out again. Yes, I did.
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584. But for a legitimate reason.
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585. There was a gun in the house, but that's not the point.
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586. The point is that, in the midst of all of this...
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587. I took on not one,
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588. but two jobs at the hospital.
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589. Yeah, which you love.
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590. Not more than you.
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591. Mm.
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592. Come back to the clinic.
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593. Do I get to boss you around?
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594. A little.
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595. Let's go upstairs.
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596. Charlie asked for you.
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597. You connected with him.
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598. I said what I had to to get him into surgery.
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599. Nah.
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600. You were your old self again.
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601. My old self...
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602. Was always there for everyone.
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603. Was giving away pieces of herself over and over.
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604. Charlie is still blind.
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605. It was a hell of a day.
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606. The blind kid didn't get me depressed.
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607. You, on the other hand...
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608. Deal with your crap
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609. before this is who you really become.
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610. DR. Hey, this is Audrey. You know what to do.
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